“Newton was mechadesh calculus.” (Weiser)
“The new math teacher was mechadesh calculus as part of the curriculum.” (Weiser)
“I can't see what mailos calculus has been mechadesh.” (Weiser)
"We must personally aspire to innovate and be mechadesh for the right reasons, but at the same time must be careful of crushing others creative insights by questioning their sincerity and motive." (source)